Erinnya lya kemiko ery’ekintu ekikendeeza ye 2-amino-4-acetamidoanisole, nga kino kye kisinga obukulu ekiwagira wakati mu kukola langi. langi ezikolebwa nga tukozesa2-amino-4-acetamidoanisole mulimu okusaasaana okunene, okusaasaana kwa bbululu, langi ku lunyiriri, n’ebirala {{5, era akatale akanene, era waliwo akatale, era waliwo akatale, era waliwo akatale akatono, era waliwo akatale akatono, waliwo akatale akatono, era waliwo akatale akatono, waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era waliwo akatale akatono, era nga kali mu butono, nga kaliko langi ya bbululu, kaliko langi, etc aliwo. .
Mu kiseera kino, waliwo enkola bbiri enkulu ez’okuteekateeka ebikozesebwa ebikendeeza: ekimu ye p-nitrochlorobenzene ng’ekintu ekitandika, era ekintu ekivaamu kifunibwa nga kiyita mu kusengejja, okukendeeza ku p-aminoanisole, p-aminoanisole acylation, nitration ne reduction; Endala etegekebwa nga okozesa 2,4-dinitrochlorobenzene nga ekintu ekisookerwako, etherification, okukendeeza n'okulonda acylation.
The first route has a long process. In the traditional process, the reduction of p-nitroanisole is carried out by a sodium sulfide process, and the reduction of 2-nitro-4-methoxyacetanilide is carried out by an iron powder process. The treatment of iron sludge residue, the nitrification process also produces a large amount of high concentration of dilute acid. Traditional sodium Enkola z’okukendeeza ku buwunga bwa sulfide n’ekyuma nazo zirina amakungula matono, okukozesa ssente ennyingi, n’omuwendo gw’ebintu ebikolebwa, ebibadde biwereddwa embeera.
Wadde ng’ekkubo ery’enkola ery’okubiri lifunze enkola eno, olw’ensonga ng’obutasobola kulongoosa makungula g’enkolagana enkulu n’enkola nnyingi ez’oku mabbali, tewali lipoota za makolero zibadde zitegeezebwa okutuusa kati.